Cheesy Pepperoni Pasta Bake Recipe

If you love a cozy, comforting pasta dish that’s cheesy, hearty, and full of that classic pepperoni punch, this Cheesy Pepperoni Pasta Bake Recipe is going to become your new go-to. I absolutely love how the gooey melted cheese combines with savory pepperoni and beef, creating a bubbly bake that’s as fun to make as it is to eat. Whether you’re looking for a simple weeknight dinner or something to impress a casual crowd, this pasta bake fits the bill perfectly.

When I first tried this recipe, it was a revelation—such an easy way to enjoy the flavors of a pizza but in a warm, casserole form that’s perfect for sharing. You’ll find that it comes together quickly, with straightforward ingredients that you likely already have. Plus, it’s easy to customize, so you can make it your own and keep everyone happy at the table.

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Ingredients You’ll Need

These ingredients come together to bring that perfect balance of cheesy richness, meaty goodness, and zesty sauce. Using rotini helps trap all that delicious flavor in every bite, while the marinated Italian seasoning adds an extra layer of warmth.

• Rotini pasta: Its curly shape holds sauce so every forkful is packed with flavor.
• Ground beef: Use lean if you prefer less grease, but a little fat adds great flavor.
• Kosher salt and pepper: Simple seasonings that bring out the beef’s natural taste.
• Pepperoni slices: The star ingredient—choose classic or spicy depending on your mood.
• Mozzarella cheese: Divided so you get melty layers and a golden cheese topping.
• Mild cheddar cheese: Adds a subtle sharpness and creamy texture.
• Marinara sauce: Go for your favorite jarred brand or homemade if you’re feeling fancy.
• Italian seasoning: A blend of herbs that tie the dish together beautifully.

Variations

I love making this Cheesy Pepperoni Pasta Bake Recipe my own by switching up ingredients based on what I have or what my family is craving. Don’t hesitate to get creative—it’s so forgiving and flexible!

• Veggie Boost: I often toss in mushrooms, bell peppers, or black olives for an extra veggie punch that sneaks in flavor and color.
• Spicy Twist: Adding red pepper flakes or using spicy pepperoni brings a nice heat that my family enjoys on cooler nights.
• Cheese Lover’s Dream: Feel free to mix in provolone or asiago for an even richer cheese experience.
• Ground Turkey Swap: For a lighter option, I sometimes swap ground beef for ground turkey—it still tastes fantastic!

How to Make Cheesy Pepperoni Pasta Bake Recipe

Step 1: Get Your Oven Ready and Cook the Pasta

Start by preheating your oven to 375°F. This step ensures the oven is at the perfect temperature when your pasta mixture is ready to bake. While the oven warms, cook your rotini pasta in salted boiling water until it’s just al dente—the pasta will finish cooking in the oven and you don’t want it mushy. Drain the pasta and set it aside.

Step 2: Cook the Ground Beef to Perfection

In a large skillet over medium-high heat, brown the ground beef alongside kosher salt and pepper. I like to stir occasionally, breaking the meat into small pieces so it cooks evenly—this usually takes about 8 to 10 minutes. Once it’s no longer pink, drain off any excess grease to keep the bake from feeling too heavy.

Step 3: Combine Pasta, Meats, Cheeses, and Sauce

Reduce the skillet heat to low and add the cooked pasta, pepperoni slices, half the mozzarella cheese, shredded cheddar, marinara sauce, and Italian seasoning. Mix everything gently but thoroughly so all ingredients get evenly coated. Once everything is mixed, transfer the entire mixture into your prepared baking dish.

Step 4: Top It Off and Bake

Sprinkle the remaining mozzarella cheese evenly over the pasta bake. This cheesy layer on top melts and bubbles, creating a gorgeous golden crust that makes this dish irresistible. Bake uncovered for 25-30 minutes, or until the cheese is bubbly and starting to brown around the edges. Let it cool for a few minutes before serving so it sets nicely.

How to Serve Cheesy Pepperoni Pasta Bake Recipe

Garnishes

I usually sprinkle some fresh chopped parsley on top before serving—it adds a pop of color and fresh flavor that balances the richness beautifully. Sometimes, a pinch of crushed red pepper flakes or a drizzle of garlic-infused olive oil also takes it up a notch.

Side Dishes

My go-to sides are a crisp green salad with a tangy vinaigrette or garlicky roasted broccoli. They add freshness that’s super welcome alongside this rich, cheesy pasta bake. A slice of crusty bread is also perfect for mopping up any leftover sauce.

Creative Ways to Present

For a fun twist at parties, I like to bake this in individual ramekins—each guest gets a personal-sized cheesy pepperoni pasta bake. It’s cute, portion-controlled, and feels special. For family dinners, a big homemade wooden board presentation with bowls of extra toppings lets everyone customize their plates.

Make Ahead and Storage

Storing Leftovers

I store leftovers in airtight containers in the fridge, where they stay great for up to 3 days. The flavors actually deepen, making next-day lunches something to look forward to. Just be sure to cool it completely before refrigerating.

Freezing

This cheesy pepperoni pasta bake freezes really well! After baking and cooling, I portion it into freezer-safe containers or wrap tightly with foil and plastic wrap, then freeze for up to 2 months. When you’re ready, just thaw in the fridge overnight before reheating.

Reheating

To reheat, I cover the dish with foil and warm it in a 350°F oven for 15-20 minutes until heated through and bubbly. This method keeps the cheese from drying out and keeps the bake moist. Microwaving works too for a quick fix, but the oven gives the best texture.

FAQs

Final Thoughts

This Cheesy Pepperoni Pasta Bake Recipe genuinely feels like a little celebration every time I make it. It’s one of those dishes that brings simple ingredients together in a way that everyone loves, whether it’s for an easy weeknight dinner or a special gathering. I hope you enjoy making it as much as I do—you can trust me, once you try it, this pasta bake will become a staple in your kitchen too!

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