Name: Creamy Chicken Alfredo Lasagna Recipe
Prep time: 20 min
Cook time: 35 min
Total time: 55 min
Cuisine: Italian-American
Ingredients: 2 tablespoons unsalted butter; 2 garlic cloves, minced; 1 cup onion, chopped; 10 ounces fresh baby spinach; 4 cups heavy cream; 1.5 cups grated Parmesan cheese; 15 ounces ricotta cheese; 1/4 teaspoon black pepper; 1 1/2 teaspoons salt; 3 cups shredded rotisserie chicken; 15 cooked lasagna noodles; 3 cups shredded mozzarella cheese

If you’re craving something rich, comforting, and downright indulgent, this Creamy Chicken Alfredo Lasagna Recipe is exactly what you need. I absolutely love how this dish combines the creamy, garlicky Alfredo sauce with tender shredded chicken and layers of cheesy lasagna noodles — it’s like all your favorite comforts wrapped into one satisfying plate. Trust me, once you try this, it’s going to become a regular in your dinner rotation!

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Why You’ll Love This Recipe

Creamy, Flavor-Packed Sauce: The Alfredo sauce is made with real cream, butter, and cheeses, giving it that luscious, velvety texture you want in every bite.
Quick and Easy Prep: Using rotisserie chicken saves hours on cooking, so you can whip this up even on a busy weeknight.
Family Friendly Comfort Food: My family goes crazy for this lasagna — it’s cheesy, filling, and perfect for picky eaters and grown-ups alike.
Great Make-Ahead Meal: You can prepare it in advance and just bake before serving, making dinner stress-free and delicious.

A white casserole dish filled with a creamy, baked spinach and cheese pasta bake, showing a golden browned top layer of melted cheese sprinkled with fresh green chopped parsley. A scoop full of the pasta bake is lifted by a metal spoon, revealing three layers: the top browned cheese layer, a thick middle creamy white sauce with bits of dark green spinach, and a bottom pasta layer with a soft, slightly uneven texture. The background features a white marbled surface with blurred white dishware, creating a clean and bright setting. photo taken with an iphone --ar 2:3 --v 7 - Creamy Chicken Alfredo Lasagna, creamy chicken alfredo lasagna, chicken alfredo lasagna, cheesy chicken lasagna, comforting pasta casserole

Ingredients You’ll Need

Each ingredient in this Creamy Chicken Alfredo Lasagna Recipe plays a big role in balance — from the fresh spinach adding a hint of color and nutrition, to the trio of cheeses creating that irresistible cheesy goodness. When shopping, I like to grab a good quality parmesan and fresh ricotta — it really lifts the flavor.

Flat lay of unsalted butter pat, two peeled garlic cloves, one cup chopped onion in a simple white ceramic bowl, fresh baby spinach leaves loose and vibrant, heavy cream in a small white ceramic bowl, grated parmesan cheese in a small white ceramic bowl, ricotta cheese dollop in a small white ceramic bowl, black peppercorns scattered neatly, coarse salt crystals in a small white ceramic bowl, shredded rotisserie chicken pile, cooked lasagna noodles stacked, shredded mozzarella cheese in a small white ceramic bowl, all arranged symmetrically on a clean white marble surface, soft natural light, photo taken with an iPhone, professional food photography style, fresh ingredients, white ceramic bowls, no bottles, no duplicates, no utensils, no packaging --ar 2:3 --v 7 --p m7354615311229779997 - Creamy Chicken Alfredo Lasagna, creamy chicken alfredo lasagna, chicken alfredo lasagna, cheesy chicken lasagna, comforting pasta casserole

Unsalted Butter: Gives that rich base flavor for sautéing garlic and onions without extra salt.
Garlic Cloves: Fresh garlic brings a warm and aromatic punch that’s essential for Alfredo sauce.
Onion: Adding chopped onions gives a subtle sweetness and depth when cooked until translucent.
Fresh Baby Spinach: Wilts nicely into the sauce and adds a fresh, green contrast to all the creamy cheese.
Heavy Cream: This is the heart of the Alfredo sauce for creaminess that feels indulgent but so worth it.
Grated Parmesan Cheese: Sharp and nutty, it’s perfect for that authentic Alfredo taste.
Ricotta Cheese: Adds a smooth, creamy texture that melts beautifully into the layers.
Black Pepper: Just a pinch to wake up the flavors without overpowering.
Salt: Enhances all the flavors, especially important because there’s no added salty meat like bacon here.
Shredded Rotisserie Chicken: The easiest way to get tender cooked chicken without extra fuss.
Cooked Lasagna Noodles: Make sure they’re cooked al dente, since they’ll cook further in the oven.
Shredded Mozzarella Cheese: Melts and browns wonderfully on top with that satisfying gooey stretch.

Note: You’ll find the complete list of ingredients, along with their exact measurements, in the printable recipe card at the bottom of this post.

Variations

I love messing around with this Creamy Chicken Alfredo Lasagna Recipe depending on the season or what’s in my fridge. Feel free to swap out ingredients to match your taste or dietary needs — there’s lots of room to make this dish your own.

Vegetable Boost: I sometimes add sautéed mushrooms or sun-dried tomatoes — the umami really plays well with the creamy sauce.
Spicy Kick: Adding a pinch of red pepper flakes to the sauce wakes things up if you want a little heat.
Low-Carb Option: Swap noodles for thin layers of zucchini or eggplant slices to lighten it up, still coated in that Alfredo goodness.
Dairy-Free Alternative: I experimented once with cashew cream and dairy-free cheeses — the texture was surprisingly close, though a bit less sharp in flavor.

How to Make Creamy Chicken Alfredo Lasagna Recipe

Step 1: Sauté and Wilt Your Aromatics and Greens

Start by melting the butter in a large skillet over medium-high heat. Toss in the minced garlic and chopped onion and cook until the onion turns translucent — about 4-5 minutes. You’ll want to keep stirring so the garlic doesn’t brown too much; burnt garlic can taste bitter. Next, add the fresh baby spinach and stir until it’s fully wilted down. This step layers in flavor and freshness right from the start!

Step 2: Build the Creamy Alfredo Sauce

Pour in your heavy cream, then stir in grated parmesan, ricotta cheese, black pepper, salt, and shredded rotisserie chicken. Keep the heat medium and bring the mixture up to a gentle simmer without boiling. The cheeses will start melting into that thick, dreamy sauce you want. Once it’s lightly bubbling, remove the skillet from the heat — this keeps the sauce from breaking or curdling.

Step 3: Layer Your Lasagna

Grab a 9 x 13 inch deep baking dish and spread a generous spoonful of the chicken Alfredo mixture on the bottom — this prevents sticking and adds flavor right away. Layer in about 5 cooked lasagna noodles (you want to cover but not overcrowd). Next, add a thick layer of Alfredo mixture and sprinkle a third of your shredded mozzarella cheese on top. Repeat this layering process two more times until all noodles and sauce are used up, finishing with mozzarella on top.

Step 4: Bake and Broil to Perfection

Cover the dish tightly with aluminum foil and pop it into a preheated 350°F oven. Bake for 35-40 minutes to let all those flavors meld and cheeses melt together. Then, uncover and broil for 2-3 minutes to get that glorious golden-brown cheese crust on top. Watch it closely here — it can go from perfect to burnt fast!

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Pro Tips for Making Creamy Chicken Alfredo Lasagna Recipe

Use Rotisserie Chicken for Speed: I discovered this trick when I first made this recipe — shredded store-bought rotisserie chicken saves so much time without sacrificing flavor.
Don’t Overboil the Sauce: Simmer gently to prevent the cream from separating, which keeps your sauce silky smooth.
Layer Generously: Don’t skimp on the Alfredo mixture between layers — that’s where the magic happens!
Watch the Broil Step Closely: Cheese browns quickly under the broiler; a minute or two can make a big difference in texture and flavor.

How to Serve Creamy Chicken Alfredo Lasagna Recipe

A close-up of a white rectangular dish filled with creamy five-layer lasagna. The top layer is golden brown melted cheese with small green parsley pieces scattered on it. Underneath, a thick creamy white sauce with bits of green herbs and pieces of soft pasta sheets can be seen. A white spatula is lifting a piece from the corner, revealing layers of white sauce, cheese, and pasta stacked evenly inside the dish. The dish is placed on a white marbled surface with some blurred background elements. Photo taken with an iphone --ar 2:3 --v 7 - Creamy Chicken Alfredo Lasagna, creamy chicken alfredo lasagna, chicken alfredo lasagna, cheesy chicken lasagna, comforting pasta casserole

Garnishes

I usually top each slice with a sprinkle of freshly chopped parsley or basil for a pop of color and freshness. Sometimes, a little extra grated parmesan right at the table adds that finishing savory note I love.

Side Dishes

My go-to sides are a crisp Caesar salad or roasted garlic green beans — the veggies add a nice contrast to this rich main dish without stealing the show.

Creative Ways to Present

For special occasions, I sometimes serve individual portions in small ramekins or cast iron skillets — it looks fancy but keeps everyone’s portion perfectly cheesy and melty. Plus, it keeps leftovers easier to reheat!

Make Ahead and Storage

Storing Leftovers

I store leftovers in airtight containers in the fridge for up to 4 days. The sauce thickens nicely overnight, so leftovers actually taste even better the next day.

Freezing

This recipe freezes really well. I assemble it in a freezer-safe dish, wrap tightly with foil, and freeze before baking. When you’re ready, just thaw overnight in the fridge and bake as usual—adding a bit more time if still partially frozen.

Reheating

Reheat leftovers in the oven at 350°F, covered with foil to keep moisture in, for about 20 minutes or until warmed through. You can also microwave single servings, but the oven keeps the cheesy layers perfectly creamy.

FAQs

Can I use fresh chicken instead of rotisserie chicken?

Absolutely! You can cook chicken breasts or thighs before shredding them for this recipe. Just be sure to season and cook them fully, then shred while still warm to mix easily into the Alfredo sauce.
Do I need to pre-cook the lasagna noodles?

Yes, this recipe calls for cooked lasagna noodles. Cooking them al dente before layering ensures they finish perfectly after baking without becoming too mushy or underdone.
Can I make this recipe dairy-free or vegan?

You can try substituting dairy with plant-based cream alternatives and vegan cheeses, but keep in mind the texture and flavor will be different. Using a homemade cashew cream sauce might get you closer to that creamy texture.
How do I store and reheat leftovers without drying them out?

Store leftovers in airtight containers and reheat covered with foil to trap moisture. Using the oven rather than a microwave helps keep the sauce creamy and the cheese from drying out.

Final Thoughts

This Creamy Chicken Alfredo Lasagna Recipe quickly became one of my family favorites because it hits all the right notes: creamy, cheesy, comforting, and easy to make. I love how it feels fancy enough for company but simple enough to enjoy any night of the week. I’m confident once you make it, you’ll be reaching for this recipe again and again — it’s kitchen magic in a casserole dish, and I’m so excited for you to try it!